Corneal Nerve Fiber Structure, Its Role in Corneal Function, and Its Changes in Corneal Diseases

Corneal Nerve Fiber Structure, Its Role in Corneal Function, and Its Changes in Corneal Diseases

Recently, in vivo confocal microscopy is used to examine the human corneal nerve fibers morphology. Corneal nerve fiber architecture and its role are studied in healthy and pathological conditions. Corneal nerves of rats were studied by nonspecific acetylcholinesterase (NsAchE) staining. NsAchE-positive subepithelial (stromal) nerve fiber has been found to be insensitive to capsaicin. Besides, ...

Prediction of Corneal Condition After Corneal Ring Implantation in Keratoconus Patients

Background: Keratoconus is a common complication among corneal defects. As a result of expeditious and extensive progress of medical science in recent decades, corneal ring implantation has turned into a successful surgical procedure to correct the vision of Keratoconus patients; however, selecting the right patient is essential in the success of the operation. The prediction of corneal conditi...

Primary Corneal Keloid

Purpose: To report the clinical presentation, histopathologic findings, and surgical treatment in a series of cases with primary corneal keloid. Case Reports: Six Iranian patients (a father and two sons, a mother and her daughter, and one isolated male patient) without any history of corneal trauma or systemic diseases were clinically and histologically evaluated for a slowly-growing, white opa...

Corneal Grafting in India: Its Difficulties

Twist2: role in corneal stromal keratocyte proliferation and corneal thickness.

PURPOSE Twist2 is a member of a family of bHLH transcription factors critical for normal mesenchymal proliferation and differentiation. In this study, the authors analyzed the role of Twist2 in the eye and cornea through examination of a Twist2 loss-of-function mouse mutant. METHODS Twist2 expression during eye development in the mouse was investigated using RT-PCR and mRNA slide in situ hybr...